QUERCETIN--Comprehensive Guide. Antioxidant, antimicrobial, antihistamine, anti-inflammatory

Summary

Highlights

• Quercetin is a bioactive flavonoid commonly found in apples, berries, and broccoli. 🌿
• It acts as an antioxidant, anti-inflammatory, antihistamine, and antimicrobial agent. 💪
• Great for fighting allergies, reducing high cholesterol, and modulating immune response. 🤒
• Quercetin enhances zinc absorption into the cells, aiding in viral defense. 🛡️
• Utilize in divided doses for allergy season or at the first sign of a cold. 🌬️

Key Takeaways

• Quercetin is a powerhouse antioxidant found in many fruits and veggies, like apples, berries, and red onions! 🍎🥦
• It offers multiple health benefits: anti-inflammatory, antimicrobial, antihistamine, and immune support. 🌟
• Perfect for managing allergies and boosting your immune system, especially when cold and flu season hits. 🤧
• You can pair it with other nutrients like vitamin C, NAC, and zinc for even stronger effects! 💪
• There are various forms of quercetin available for better absorption, so choose wisely! 🧐

Overview

Chapters

• 00:00 - 00:30: Introduction to Quercetin The chapter introduces the topic of quercetin, focusing on its antioxidant properties. Dr. Jin Sung, known for integrating clinical excellence with outstanding results, leads the discussion following a previous video on NAC (N-acetylcysteine). This video generated interest due to the antioxidant nature of NAC, setting the stage to explore quercetin, another powerful antioxidant. The chapter aims to delve into the features and uses of quercetin as an antioxidant, potentially paralleling or complementing the benefits of NAC.
• 00:30 - 02:00: Properties of Quercetin Quercetin is recognized for its diverse properties, including anti-inflammatory, antimicrobial, immune enhancing or modulating, and antihistamine effects. It is a bioactive flavonoid commonly present in numerous fruits and vegetables such as apples, berries, broccoli, grapes, nuts, onions (particularly the red variety), bell peppers, and tomatoes.
• 02:00 - 03:00: Clinical Applications of Quercetin The chapter explores the clinical applications of Quercetin, focusing on multiple health conditions. It outlines the benefits of Quercetin in managing allergies, where it can be combined with Bromelain and Stinging Nettle Leaf to enhance antihistamine effects. Quercetin's potential role in addressing viral infections, neurocognitive changes, cardiovascular disease, and diabetes is also highlighted, though the specifics of these applications are not detailed in the provided transcript.
• 03:00 - 04:00: Dosage and Tolerance The chapter titled 'Dosage and Tolerance' discusses the benefits of supplements such as Knack (n-acetylcysteine). It highlights their role in supporting neurocognitive function, reducing inflammation, and providing cardioprotective effects. Specifically, these supplements have been noted for their cholesterol-modulating benefits, including reducing high cholesterol and lowering high blood pressure.
• 04:00 - 06:00: Usage During Allergy Season The chapter discusses the benefits of quercetin, particularly during allergy season, highlighting its anti-inflammatory effects and its ability to decrease cardiovascular risk and neurocognitive changes. It notes that quercetin is generally well-tolerated, but advises caution for individuals with kidney disease, especially those with very low GFR levels.
• 06:00 - 08:00: Types of Quercetin for Better Absorption The chapter discusses the recommended dosages and frequency of quercetin intake for optimal absorption and effectiveness. It suggests that quercetin is generally well-tolerated in doses ranging from 500 to 1000 milligrams, taken in divided doses two to four times per day. It emphasizes the importance of multiple doses throughout the day due to quercetin's half-life, which is about three and a half to seven hours, to maximize its beneficial effects.
• 08:00 - 13:00: Additional Nutrients and Diet for Inflammation The chapter discusses nutritional strategies during allergy season and early signs of illness. It emphasizes the use of quercetin to reduce histamine effects and as a preventative measure at the onset of a cold or flu. Quercetin's role as a zinc ionophore is also highlighted, meaning it helps enhance the transport of zinc into the cells.

QUERCETIN--Comprehensive Guide. Antioxidant, antimicrobial, antihistamine, anti-inflammatory Transcription

• 00:00 - 00:30 [Music] welcome back this is Dr Jin sung we're at clinical Excellence meets excellent results a couple of weeks ago I made a video on NAC or Knack and acetylcysteine it generated a lot of interest because of the antioxidant properties of it today we're going to talk about quercetin which also has a very high antioxidant activity so let's go into some of the features of quercetin question can be used as a antioxidant
• 00:30 - 01:00 anti-inflammatory antimicrobial as well as a immune enhancing or immune modulating supplement as well as a antihistamine okay so what is it it's a bioactive flavonoid found in lots of fruits and veggies so things like apples berries broccoli grapes nuts onions especially the red variety bell peppers tomatoes Etc okay there's
• 01:00 - 01:30 more Foods than just what I listed there so the clinical applications are things for allergies viruses neurocognitive changes as well as cardiovascular disease and diabetes now in terms of allergies you can use quercetin with things like bromelin and stinging nettle Leaf to enhance antihistamine effects okay with viruses you can use it with things
• 01:30 - 02:00 like Knack or n acetylcysteine and other supplements supplements which I will list a little later on also it helps neurocognitive changes because it helps improve inflammation and also has a cardio protective effect so in terms of cardiovascular effects it has a cholesterol modulating effect so it reduces high cholesterol it reduces blood pressure or high blood pressure as
• 02:00 - 02:30 well as anti-inflammatory effects so all those things combined has a decrease in cardiovascular risk as well as neurocognitive changes now there are different forms of quercetin that you can utilize right I just listed a few there the quercetin is usually very well tolerated right only people who need to be cautious are usually people who have kidney disease whether GFR is very low
• 02:30 - 03:00 so if it's well tolerated we can use anywhere from 500 to 1 000 milligrams in divided doses right and two to four times per day so you can take 500 milligram capsules two to four times per day or up to a thousand milligrams two to four times a day the half-life is about three and a half to seven hours that's why you want to dose multiple times throughout the day to have the most positive effect
• 03:00 - 03:30 so when you when you're in allergy season you want to use it more frequently to knock down the histamine effects or you can use it prophylactically very early on in terms of let's say getting a cold or the flu right the first signs and symptoms is when you want to really hit it hard with quercetin now it also has a zinc ionophore effect what that means is that quercetin enhances the transport of zinc into the
• 03:30 - 04:00 cell membrane that's why it can be a very important nutrient in terms of fighting viruses okay now there are other nutrients that can enhance viral replication or help you help the immune system fight off viruses foreign in terms of the first signs of let's say a cold or or a viral pneumonia or any
• 04:00 - 04:30 types of viruses that you may catch during the winter months right things like vitamin C vitamin A is very important zinc as like I said quercetin is a zinc ionophore astragalus extracts echinacea licorice licorice root extracts mataki mushrooms lemon balm extracts and I also like cordyceps for a lung
• 04:30 - 05:00 function so you can use these in combination at the first sign of catching a cold or the flu or the first signs of runny nose or congestion and you can ward off these conditions much faster in the disease process or the infection process of a virus today we're going to talk about quercetin and seasonal allergies here in the Northeast the trees and flowers are blooming and there's pollen
• 05:00 - 05:30 everywhere and this is when people get allergic rhinitis runny nose itchy eyes Etc so how do we combat that so during the season we like to use quercetin quercetin consistently demonstrates the greatest activity among the flavonoids in animal studies for allergies or release of histamine so it prevents modulates the release of histamine from basophils and mast cells
• 05:30 - 06:00 those are the two cells that release histamine into our bloodstream creating that itchy runny nose sensation foods high in quercetin apples berries broccolis cauliflower cabbage grapes nuts red onions in particular bell peppers green tea if you cook these Foods it reduces the level of quercetin so you want to have them raw when possible
• 06:00 - 06:30 question also has other effects antioxidant anti-inflammatory anti-cancer antimicrobial and it's immune modulating quercetin works like a zinc ionophore right it pushes zinc into the cells so it helps in the sense of fighting viruses it prevents or inhibits viral replication so zinc ionophores like quercetin can be utilized during the flu
• 06:30 - 07:00 season all right [Music] I've actually made a separate video on quercetin and the benefits so you want to watch that video and I'll link it below so question 10 and seasonal allergies there are different forms and some absorb better than others quercetin itself doesn't absorb readily so there are different forms that can be utilized alcone anhydrous
• 07:00 - 07:30 you can use a form called Lexington formulation it's called a phytosome where they encapsulate into a fat basically so it absorbs better up to 20 times better than just regular forms of quercetin there's quercetin dihydride hydrate and then there's also a formula called enzymatically modified isoquist trend emiq
• 07:30 - 08:00 and that's also more absorbable into our system half-life of course attendance three and a half to seven and a half hours so you should take quercetin and divided doses you can take anywhere from 500 to 1000 milligrams two to four uh divided doses during the day just during Peak allergy season you don't have to take this for long periods of time it's just more for
• 08:00 - 08:30 um managing the symptoms of allergies so you start with the smallest dosage right you go 500 milligrams twice a day see if it makes a benefit if it doesn't you can bump it up to 500 milligrams four times a day and then so forth so you don't want what start with the highest dose you want to start with the lowest dosage and see what's going to be beneficial for you now there are other nutrients that are helpful for modulation in terms of
• 08:30 - 09:00 circulation and inhibiting histamine release stinging nettle butterbur extracts mangosteen extract Ginger is another good one vitamin C obviously is good for immune system and vitamin D so if you can combine quercetin and you can add some of these in and you don't have to add all of them but add some of them to see if you can have the most benefit during an allergy season
• 09:00 - 09:30 now what I find most beneficial for patients is that when they get home they shower right rinse off all the pollen off their body so they don't carry it into their bed also an anti-inflammatory diet can also be quite beneficial because it reduces the inflammatory load in our body therefore if you do get allergens into our system you don't have any over active or exuberant reaction to pollen
• 09:30 - 10:00 so those are some of the strategies today we're going to talk about acute inflammation and quenching the fire putting that fire out last video we talked about the inflammatory markers that you can utilize to see if you have inflammation today we're going to talk about supplementation and dietary recommendations so number one NAC or n acetylcysteine you can utilize 1000 milligrams two times a day to decrease free radical activity as you
• 10:00 - 10:30 know NAC is a precursor to glutathione and is a very important antioxidant quercetin also known to quench histamine reaction can use it for inflammatory processes 1000 milligrams twice a day helps to decrease leukotrienes Resveratrol 1000 milligrams two times a day two to three times a day decreases NF cap a b turmeric or curcurement
• 10:30 - 11:00 you can use 1000 milligrams up to three times a day also decreasing NF capital B fish oil APA DHA in their Q phases you can use two thousand milligrams three to five times a day it will increase anti-inflammatory prostaglandins and decrease inflammatory carcinoids so it helps the inflammatory process by dampening it these supplements you can utilize also for people who have chronic inflammation
• 11:00 - 11:30 in smaller doses so if you if I recommend one thousand milligram twice a day on on a supplement if you have chronic inflammation or chronic issues or even maintenance doses you can use 1 000 milligram once a day or 500 milligrams twice a day so you want to reduce the dosages but if you do have chronic health issues and you really have a lot of problems you probably want to work with the health care provider who can you know kind of fine-tune the
• 11:30 - 12:00 dosage for you for these types of supplements okay so anti-inflammatory what about diet definitely want to reduce sugar or carbohydrates because sugar will Spike insulin and Insulin spikes can create inflammatory processes partially hydrogenated fats you want to reduce shellfish temporarily red meats and obviously processed foods what you want to increase is increases
• 12:00 - 12:30 water fatty fish and high antioxidant Foods okay cold showers or cold ice plunges can increase endorphins increased growth factor increase circulation and decrease inflammatory cytokines so you can use this combination in a very short period of time maybe up to two weeks and then go down into what we call maintenance Doses and that maintenance dose will be dependent on
• 12:30 - 13:00 your health needs on the supplementation I've actually made videos on each one of them explaining what it does so you want to watch those videos I'll link it below so you can watch those and give yourself an idea of how those things work in combination all right my name is Dr Jen sung we're a clinical Excellence meets excellent results and we'll see you guys next week on the healthy side have an awesome day